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Poster
Other/Multi
AACR 2024 | April 5-10, 2024
Other/Multi
A phase 1/2, first-in-human study of DS-3939a in patients with advanced solid tumors: A new DXd ADC targeting TA-MUC1
Noboru Yamamoto
Poster
HER3-DXd
AACR 2024 | April 5-10, 2024
Other/Multi
An evaluation of patritumab deruxtecan (HER3-DXd, U3-1402) against pediatric PDX models for hepatoblastoma and rhabdomyosarcoma – a report from the NCI PIVOT program
Raushan Kurmasheva
Poster
T-DXd
AACR 2024 | April 5-10, 2024
Breast Cancer
Concordance between the DESTINY-Breast04 clinical trial assay (4B5[CDx]) and other HER2 IHC assays for HER2-low breast cancer in real-world practice: First phase of a large-scale, multicenter global ring study
Hans-Ulrich Schildhaus
Poster
Dato-DXd
AACR 2024 | April 5-10, 2024
Other/Multi
Dato-DXd mediates anti-tumor activity in preclinical TROP2-expressing intracranial tumor model
Kristen Jones
Oral
Other/Multi
AACR 2024 | April 5-10, 2024
Other/Multi
DS-3939a, a novel TA-MUC1-targeting antibody-drug conjugate (ADC) with a DNA topoisomerase I inhibitor DXd, exhibits potent antitumor activity in preclinical models
Mayuko Yukiura
Poster
T-DXd
AACR 2024 | April 5-10, 2024
Other/Multi
Dual immune checkpoint blockade enhances the anti-tumor activity of trastuzumab deruxtecan in preclinical models
Liam Jenkins
Poster
Dato-DXd
AACR 2024 | April 5-10, 2024
Gastric Cancer
Evaluating the combination of datopotamab deruxtecan (Dato-DXd) with saruparib (AZD5305), a highly potent, PARP1-selective inhibitor, in preclinical models
Gopi Patel
Poster
Dato-DXd
AACR 2024 | April 5-10, 2024
Lung Cancer
Functional profiling in lung tumor explants show contributions of the tumor microenvironment to response of Dato-DXd ex vivo
Satoru Yasuda
Poster
I-DXd
AACR 2024 | April 5-10, 2024
Other/Multi
In vivo efficacy of B7-H3 (CD276)-directed antibody-drug conjugate (ADC) ifinatamab deruxtecan (I-DXd; DS-7300a): An update from the pediatric preclinical in vivo testing (PIVOT) program
Richard Gorlick
Poster
T-DXd
AACR 2024 | April 5-10, 2024
Lung Cancer Other/Multi
Leveraging advanced human lung models to explore mechanisms underlying T-DXd-associated interstitial lung disease (ILD)
Ingrid A. Lua
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