Valemetostat
Hematology
Enhancer of zeste homolog 1/2 dual inhibitor valemetostat outperforms enhancer of zeste homolog 2-selective inhibitors in reactivating latent HIV-1 reservoirs ex vivo
Sedohara A, Koibuchi T, Yamagishi M, et al.
Front Microbiol. 2025 Apr;16:1581330. doi: 10.3389/fmicb.2025.1581330.
Other/Multi
Breast Cancer
Accuracy of human epidermal growth factor receptor 2 (HER2) immunohistochemistry scoring by pathologists in breast cancer, including the HER2-low cutoff
Wróbel A, Vandenberghe M, Scott M, et al.
Diagn Pathol. 2025 Apr;20(1):35. doi: 10.1186/s13000-025-01624-3.
Other/Multi
Breast Cancer
Treatment patterns and associated outcomes among patients with HER2+ metastatic breast cancer in the United States: An observational cohort study
Lam C, Varghese D, Collins J, et al.
Oncologist. 2025 Apr;30(4):oyae280. doi: 10.1093/oncolo/oyae280.
Edoxaban
Cardiovascular - AF
Real-world evidence comparing oral anticoagulants for NVAF in Europe: A systematic review and network meta-analysis
Cichewicz A, Jawla S, Zuchinali P, et al.
Future Cardiology, 21(6), 371–390. https://doi.org/10.1080/14796678.2025.2484119
Other/Multi
Breast Cancer
Treatment patterns and outcomes in HER2-low metastatic breast cancer patients previously treated with chemotherapy: A US real-world cohort study
Modi S, Zhang S, Byng D, et al.
Breast Cancer Res Treat. 2025 Jun;211(2):351-362. doi: 10.1007/s10549-025-07649-y.
Edoxaban
Cardiovascular - AF
Edoxaban treatment in routine clinical practice is highly concordant with the 2020 European Society of Cardiology atrial fibrillation guidelines: Results from the noninterventional Global ETNA-AF programme
Morrone D, Dinshaw L, de Souza JAG, et al.
Eur Heart J Open. 2025 Mar;5(2):oeaf004. doi: 10.1093/ehjopen/oeaf004.
T-DXd
Breast Cancer
A retrospective study to investigate the prevalence and describe the clinicopathological characteristics, treatments, and outcomes of HER2-low breast cancer in Taiwan
Lee K-T, Huang P-H, Hsu C-Y, et al.
Cancer Treat Res Commun. 2025 Mar;43:100893. doi: 10.1016/j.ctarc.2025.100893.
Quizartinib
Hematology
Impact of hematopoietic cell transplantation and quizartinib in newly diagnosed patients with acute myeloid leukemia and FMS-like tyrosine kinase 3-internal tandem duplications in the QuANTUM-First trial
Schlenk RF, Montesinos P, Kim H-J, , et al.
Haematologica. 2025;110(9):2024-2039. doi: 10.3324/haematol.2024.286623
Dato-DXd
Breast Cancer
Lung Cancer
Other/Multi
Prophylaxis, clinical management, and monitoring of datopotamab deruxtecan-associated oral mucositis/stomatitis
Meric-Bernstam F, Bardia A, Bossi P, et al.
Oncologist. 2025 Mar;30(3):oyaf031. doi: 10.1093/oncolo/oyaf031.
Dato-DXd
Lung Cancer
Datopotamab deruxtecan versus docetaxel for previously treated advanced or metastatic non-small cell lung cancer: The randomized, open-label phase III TROPION-Lung01 study
Ahn M-J, Tanaka K, Paz-Ares L, et al.
J Clin Oncol. 2025;43(3):260-272. doi: 10.1200/JCO-24-01544.