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HER3-DXd
Lung Cancer
Cost of early progression: Patients with epidermal growth factor receptor mutated metastatic non-small-cell lung cancer
Princic N, Marrett E, Kwong Wubghan J, et al.
Future Oncol. 2024. doi: 10.1080/14796694.2024.2370186.
T-DXd
Lung Cancer
Trastuzumab deruxtecan in HER2-mutant non-small-cell lung cancer: A plain language summary of the DESTINY-Lung01 study
Smit EF.
Future Oncol. 2024:1-11. doi: 10.1080/14796694.2024.2355724.
HER3-DXd
Breast Cancer
Patritumab deruxtecan in HER2-negative breast cancer: Part B results of the window-of-opportunity SOLTI-1805 TOT-HER3 trial and biological determinants of early response
Brasó-Maristany F, Ferrero-Cafiero JM, Falato C, et al.
Nat Commun. 2024;15(1):5826. doi: 10.1038/s41467-024-50056-y.
Edoxaban
Cardiovascular - AF
Association of D-dimer level with thrombotic events, bleeding, and mortality in Japanese patients with solid tumors: A Cancer-VTE registry subanalysis
Nakamura M, Sakon M, Sasako M, et al.
Int J Clin Oncol. 2024;29:407-416.
Edoxaban
Cardiovascular - AF
Dose reduction of edoxaban in patients 80 years and older with atrial fibrillation: Post hoc analysis of the ENGAGE AF-TIMI 48 randomized clinical trial
Zimerman A, Braunwald E, Steffel J, et al.
JAMA Cardiol. 2024:e241793. doi: 10.1001/jamacardio.2024.1793. Epub ahead of print.
T-DXd
Breast Cancer
Trastuzumab deruxtecan versus trastuzumab emtansine in Asian patients with HER2-positive metastatic breast cancer
Iwata H, Xu B, Kim S-B, et al.
Cancer Sci. 2024. doi: 10.1111/cas.16234.
Edoxaban
Cardiovascular - AF
R2-CHA2DS2-VASc score for cardiovascular event prediction after bioprosthetic valve replacement: Subanalysis from the BPV-AF registry
Sano M, Takegami M, Amano M, et al.
Circ Rep. 2024;6(8):341-348. doi: 10.1253/circrep.CR-24-0033.
Valemetostat
Lung Cancer
A phase I/II study of valemetostat (DS-3201b), an EZH1/2 inhibitor, in combination with irinotecan in patients with recurrent small cell lung cancer
Choudhury NJ, Lai WV, Makhnin A, et al.
Clin Cancer Res. 2024. doi: 10.1158/1078-0432.CCR-23-3383. Epub ahead of print.
Dato-DXd, DS-1103, Other/Multi
Other/Multi Tumor-agnostic
Blockade of SIRPα-CD47 axis by anti-SIRPα antibody enhances anti-tumor activity of DXd antibody-drug conjugates
Sue M, Tsubaki T, Ishimoto Y, et al.
PLoS One. 2024;19(6):e0304985.
Edoxaban
Cardiovascular - AF
Application of the win ratio method in the ENGAGE AF-TIMI 48 trial comparing edoxaban with warfarin in patients with atrial fibrillation
Bergmark BA, Park J-G, Hamershock RA, et al.
Circ Cardiovasc Qual Outcomes. 2024;17(7):e010561.
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