Poster
Other/Multi
ASCO 2025 | May 30-June 3,2025
Lung Cancer Other/Multi
A phase 1, first-in-human study of DS-2243, an HLA-A*02/NY-ESO–directed bispecific T‑cell engager, in patients with advanced solid tumors
Sandra P. D'Angelo
Poster
T-DXd
ASCO 2025 | May 30-June 3,2025
Gastric Cancer
An open-label, randomized, multicenter, phase 3 study of trastuzumab deruxtecan (T-DXd) + chemotherapy ± pembrolizumab versus chemotherapy + trastuzumab ± pembrolizumab in first-line metastatic HER2+ gastric or gastroesophageal junction cancer: DESTINY-Gastric05
Kohei Shitara
Poster
T-DXd
ASCO 2025 | May 30-June 3,2025
Gastric Cancer
ARTEMIDE-Gastric01: A phase 3 randomized study of rilvegostomig with fluoropyrimidine and trastuzumab deruxtecan as first-line treatment for locally advanced or metastatic HER2-positive gastric or gastroesophageal junction cancer
Rui-Hua Xu
Poster
T-DXd
ASCO 2025 | May 30-June 3,2025
Breast Cancer
Electronic patient-reported outcomes with vital signs monitoring versus usual care during trastuzumab deruxtecan treatment for metastatic breast cancer: Updated results from the PRO-DUCE study
Yuichiro Kikawa
Oral
T-DXd
ASCO 2025 | May 30-June 3,2025
Breast Cancer
Exploratory biomarker analysis of trastuzumab deruxtecan (T-DXd) vs physician’s choice of chemotherapy (TPC) in HER2-low/ultralow, hormone receptor–positive (HR+) metastatic breast cancer (mBC) in DESTINY-Breast06
Rebecca Dent
Poster
Dato-DXd
ASCO 2025 | May 30-June 3,2025
Lung Cancer
First-line datopotamab deruxtecan (Dato-DXd) + rilvegostomig in advanced or metastatic non-small cell lung cancer: Results from TROPION-Lung04 (cohort 5)
Saiama N. Waqar
Poster
HER3-DXd
ASCO 2025 | May 30-June 3,2025
Breast Cancer
HERTHENA-Breast03: A phase 2, randomized, open-label study evaluating neoadjuvant patritumab deruxtecan (HER3-DXd) plus pembrolizumab before or after pembrolizumab plus chemotherapy for early-stage triple-negative breast cancer (TNBC) or hormone receptor–low positive (HR-low+)/human epidermal growth factor receptor 2–negative (HER2−) breast cancer
Joyce O'Shaughnessy
Poster
I-DXd
ASCO 2025 | May 30-June 3,2025
Tumor-agnostic
IDeate-PanTumor02: A phase 1b/2 study to evaluate the efficacy and safety of ifinatamab deruxtecan (I-DXd) in patients with recurrent or metastatic solid tumors
Takahiro Kogawa
Poster
I-DXd, HER3-DXd
ASCO 2025 | May 30-June 3,2025
Lung Cancer
KEYMAKER-U01 substudy 01A: Phase 1/2 study of pembrolizumab plus ifinatamab deruxtecan (I-DXd) or patritumab deruxtecan (HER3-DXd) with or without chemotherapy in untreated stage IV non–small-cell lung cancer
Charu Aggarwal
Poster
I-DXd
ASCO 2025 | May 30-June 3,2025
Other/Multi
KEYMAKER-U06 Substudy O6E: A phase 1/2 open-label, umbrella platform study of ifinatamab deruxtecan in combination with pembrolizumab with or without chemotherapy for first-line treatment of advanced esophageal squamous cell carcinoma
Ken Kato
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